tert-Butyl 2,2,2-trichloroacetimidate

CAS 98946-18-0, Cat. No EN300-100400

Reagent for preparation of t-butyl esters and ethers

tert-Butyl 2,2,2-trichloroacetimidate is a reagent for for preparation of t-butyl esters and ethers in soft conditions with high yields. It is a white solid soluble in organic solvents, preferably nonpolar ones especially cyclohexane (polar solvents promote ionization and decomposition). After the procedure of purification, the yield of the reaction is usually high (about 80‑90 %). In the case of formations of ethers less hindered hydroxy group is preferable for reaction, and in the case of secondary alcohols 2 equivalent of reagent is needed for a more effective reaction.

Synonyms: 2,2,2-Trichloroacetimidic acid tert-butyl ester; 2,2,2-Trichloroethanimidic acid tert-butyl ester; O-tert-Butyl trichloroacetimidate; tert-Butyl 2,2,2-trichloroacetimidate; tert-Butyl 2,2,2-trichloroethanimidate; tert-Butyl trichloroacetimidate