Acetoxime O-(2,4,6-trimethylphenylsulfonate)

CAS 81549-07-7, Cat. No EN300-7358500

Electrophilic aminating reagent for Grignard reagents

Acetoxime O-(2,4,6-trimethylphenylsulfonate is a reliable reagent for electrophilic aminating reaction of Grignard reagents. It is a stable solid soluble in ether, THF, and partial in benzene. The use of Copper(I) Iodide or MgCl₂ as a catalyst in the amination of aryl Grignard reagents decreases the reaction time remarkably and/or increases the yield.

Synonyms: (Propan-2-ylideneamino) 2,4,6-trimethylbenzenesulfonate; 2-Propanone, O-[(2,4,6-trimethylphenyl)sulfonyl]oxime

Selected publication

1. Acetoxime O -(2,4,6-Trimethylphenyl) Sulfonate.

Erdik E. Encyclopedia of Reagents for Organic Synthesis 2001. DOI: 10.1002/047084289X.ra019